WASHINGTON (news agencies) — Rural cancer patients may miss out on cutting-edge treatments in Utah. Therapies for intellectual disorders could stall in Maryland. Red states and blue states alike are poised to lose jobs in research labs and the local businesses serving them.
Ripple effects of the Trump administration’s crackdown on U.S. biomedical research promise to reach every corner of America. It’s not just about scientists losing their jobs or damaging the local economy their work indirectly supports — scientists around the country say it’s about patient health.
“Discoveries are going to be delayed, if they ever happen,” said Dr. Kimryn Rathmell, former director of the National Cancer Institute.
It’s hard for patients to comprehend how they could lose an undiscovered cure.
Yet “all the people out there who have, you know, sick parents, sick children, this is going to impact,” said neuroscientist Richard Huganir of Johns Hopkins University.
The administration’s unprecedented moves are upending the research engine that has made the U.S. “the envy of the world in terms of scientific innovation,” said Georgetown University health policy expert Lawrence Gostin.
Among the biggest blows, if it survives a court challenge: Massive cuts in funding from the National Institutes of Health that would cost jobs in every state, according to an analysis by media with assistance from the nonprofit United for Medical Research.
That’s on top of mass firings of government workers, NIH delays in issuing grants and uncertainty about how many already funded studies are being canceled under the president’s anti-diversity executive orders.
Earlier this week, lawmakers pressured Dr. Jay Bhattacharya, the nominee to become NIH director, about the turmoil. Bhattacharya said if confirmed, he’d look into it to ensure scientists employed by and funded by the agency “have resources to do the lifesaving work they do.”
Patients who live in rural counties are 10% more likely to die of their cancer than those living in metropolitan areas, said Neli Ulrich of the University of Utah’s Huntsman Cancer Institute.
A third of patients travel more than 150 miles for care at the Salt Lake City cancer center. But for patients even further away — in Idaho, Montana, Nevada and Wyoming — because it’s also the regional hub for NIH-funded studies of new treatments.
So Ulrich’s center helps train local doctors to do at least some of the blood tests and other steps of clinical trials that let faraway patients participate without traveling — a program threatened if her university loses tens of millions in NIH cuts.
The issue: Most of the NIH’s budget — more than $35 billion a year — goes to universities, hospitals and other research groups. The grants are divided into “direct costs” — covering researchers’ salaries and a project’s supplies — and “indirect costs,” to reimburse other expenses supporting the work such as electricity, maintenance and janitorial staff, and safety and ethics oversight.
NIH directly negotiates with research groups, a process that grants managers say requires receipts and audits, to set rates for those indirect expenses that can reach 50% or more. But the Trump administration now plans to cap those rates at 15%. The administration estimates it would save the government $4 billion a year but scientists say it really means they’ll have to stop some lifesaving work.
They are “real expenses, that’s the critical point – they are not fluff,” said Ulrich. Using separate cancer center funds to cover those costs would threaten other “activities that are really important to us in serving our communities across the mountain West.”
A federal judge has blocked the move but until the court fight is done researchers aren’t sure what they can continue to afford.
NIH grants divided between researchers in every state in 2023 supported more than 412,000 jobs and $92 billion in new economic activity, according to a yearly report from United for Medical Research that often is cited as Congress sets the agency’s budget.
The news agencies tallied how much money would have been lost in each state under a 15% cap on those grants’ indirect costs. Those lost dollars alone would have cost at least 58,000 jobs, concluded an analysis assisted by Inforum, a nonpartisan economic consulting firm that conducts UMR’s economic impact reports.
Consider Hopkins, which runs about 600 NIH-funded clinical trials plus other laboratory research and is Baltimore’s largest private employer. “If we can’t do science and we can’t support the science, we can’t support the surrounding community either,” Huganir said.
Huganir studies how the brain stores memory as people learn when he discovered a gene that, when mutated, causes certain intellectual disabilities.
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